
Drug cutoff levels are the minimum concentrations of drugs or
metabolites that must be present in specimens, before labs will
report the drug testing results as positive. How much of a drug
labs can detect depends on drug detection times, frequency of
use, type of specimen, drug testing method, metabolism, and other
factors.
Labs that follow the Mandatory Guidelines for Federal Workplace
Drug Testing Programs published by the Substance Abuse and Mental
Health Services Administration (SAMHSA), first conduct one or
more initial screens followed by confirmatory tests. The approved
methods for urine analysis are one or more types of immunoassay
screens, confirmed by gas chromatography and mass spectrometry.
If you test below the drug cutoff levels on the initial screens,
the lab cannot report it as positive or continue with the confirmatory
tests. If you test above them on the initial screens, but below
them on the confirmatory test, the lab still cannot report it
as positive.
The tables below are compiled from public-domain information
in the Mandatory Guidelines for Federal Workplace Drug Testing
Programs. They are for urine analysis of the commonly-abused types
of drugs known as the "SAMHSA Five."
|
Initial Drug Cutoff Levels |
| Drug |
Nanograms per Milliliter (ng/ml) |
| Marijuana metabolites |
50 |
| Cocaine metabolites |
150 |
| Opiate metabolites 1 |
2000 |
| Phencyclidine (PCP) |
25 |
| Amphetamines 2 |
500 |
| 1 Labs are permitted
to initial test all specimens for 6-acetylmorphine
at a 10 ng/ml cutoff
2 Target analyte must be d-methamphetamine
and the test must significantly cross-react with MDMA,
MDA, and MDEA |
|
|
Confirmatory Drug Cutoff Levels |
| Drug |
Nanograms per Milliliter (ng/ml) |
| Marijuana metabolite 1 |
15 |
| Cocaine metabolite 2 |
100 |
| Opiates
Morphine
Codeine
6-acetylmorphine 4 |
2000
2000
10
|
| Phencyclidine (PCP) |
25 |
| Amphetamines
Amphetamine
Methamphetamine 3
MDMA (Ecstasy)
MDA
MDEA |
250
250
250
250
250
|
| 1 Delta-9-tetrahydrocannabinol-9-carboxylic
acid
2 Benzoylecgonine
3 Specimen must also contain d-amphetamine
at a concentration > 100 ng/ml
4 Labs test for 6-acetylmorphine when the
morphine concentration exceeds 2,000 ng/ml |
|
ote: As of September 3, 2001, SAMHSA last revised
these cutoff levels in 1998 and considers them sound. Other government
entities might have their own specifications that differ from
those above.
|